Avengers: Endgame may earn as much as $350 million domestically in its opening weekend. More than a decade ago when Kevin Feige and company launched the Marvel Cinematic Universe (building its foundation on arguably second-tier comic book characters), a lot of people felt the master plan was overly ambitious. Never before had anything like this been attempted in the film industry, but Marvel swung for the fences. Back in 2012, The Avengers became a massive critical and commercial success, firmly establishing the MCU as one of the top franchises in the business.

Nowadays, Marvel is in a position where they virtually can do no wrong. Prior to Endgame opening, the 21 films in the franchise widely expected to rewrite the box office record books during its opening weekend. But even the rosiest optimist probably didn't see this coming.

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According to Infinity War's $257.6 million from last year.

In a single day, Endgame has outgrossed all but three movies released so far in 2019. As of this writing, it trails Endgame sold five times as many tickets on Fandango. The signs were there that this was going to be a massive event nobody wanted to miss out on.

As crazy as this sounds, it's not outside the realm of possibility Endgame makes $1 billion this weekend. The film is already at $643.7 million globally, and only the earnings up until Friday, April 26 have been ed for. This illustrates the sheer magnitude of the MCU and how big it's become. Audiences have seen multiple bona fide cinematic events this decade (including the ballyhooed return of the Star Wars franchise), and none of them could come close to Endgame. It truly is the premier movie release of an entire generation and is something that will never be duplicated. Obviously, Endgame won't be the last MCU installment, but if it was, this would be a great note to go out on.

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Source: Exhibitor Relations