Netflix in September 2017. The show was so well-received by critics that it continued with a second and third season along with a Valentine’s Day special episode before being renewed through to a sixth season.
Big Mouth follows a group of teens as they deal with puberty and more with the help of their Homone Monsters, although they mostly create more problems. Big Mouth has been a hit thanks to its humor, relatable characters and situations, and its approach to sexuality, puberty, mental health, social issues, and more. The series hasn’t been afraid to address controversial or “taboo” topics, name drop other companies, and even mock itself, as it’s highly self-aware. Now, a bit over a year since season 3 was released, Big Mouth is back with a fourth season, along with new struggles, topics to explore, and threats.
Season 4 will see Jessi, Nick, and Andrew going to camp, where Nick and Andrew’s friendship will continue to crumble. In addition to that, Jessi will have to deal with adapting to a new city and with more changes in her body, while Missy goes through a makeover. The group will also come across Tito, the Anxiety Mosquito, who will put their worlds upside down. Big Mouth season 4 will see the return of the main cast and will welcome new voices, ready to the crazy ride that is puberty. Here’s the cast and characters guide for Big Mouth season 4 and what the voice actors look like.
Nick Kroll as Nick Birch, Maurice, Coach Steve, Lola, & More
Nick Kroll returns as the voice of Nick Birch, hormone monster Maurice, Coach Steve, and Lola Ugfuglio Skumpy. In past seasons, Kroll also lent his voice to a variety of guest characters, such as the Statue of Liberty, a ladybug, and Sylvester Stallone, to name just a few, so expect to hear his voice in new, minor characters through season 4. Kroll has appeared in a number of movies and TV shows, and has also voiced a variety of characters, though he’s best known for his work in Kroll Show and Parks & Recreation, where he played “The Douche”.
John Mulaney as Andrew Glouberman
John Mulaney voices Nick’s best friend Andrew Glouberman, who is often accompanied by Maurice, his hormone monster. Mulaney is best known for his stand-up comedy and for his work as a writer on Saturday Night Live. Mulaney appeared in Kroll Show as George St. Geegland and has voiced various characters throughout his career, most notably Peter Porker/Spider-Ham in Spider-Man: Into the Spider-Verse.
Jessi Klein as Jessi Glaser
Jessi Klein voices Jessi Glaser, a friend of Nick, Andrew, and Missy, and who has Connie as her hormone monstress. Klein is a writer, actress, and stand-up comedian, who worked as a director of development for Comedy Central, where she helped develop various TV shows, such as Chappelle’s Show and Stella, and was the head writer and executive producer of Inside Amy Schumer.
Jason Mantzoukas as Jay Bilzerian
Jason Mantzoukas lends his voice to Jay Bilzerian, a friend of the above-mentioned characters and an amateur magician. In previous seasons, Mantzoukas also voiced Guy Bilzerian (Jay’s dad) as well as the ghost of Socrates. Mantzoukas played Tick Tock Man in The Good Place.
Jenny Slate and Ayo Edebiri as Missy Foreman-Greenwald
Jenny Slate voices Missy Foreman-Greenwald through Big Mouth season 4 except for the last two episodes, where Mona-Lisa Saperstein), and starred in the movie Obvious Child. She has also voiced Tammy Larsen in Bob’s Burgers, Harley Quinn in The Lego Batman Movie, and Valerie Da Vinci in Despicable Me 3. Edebiri is a stand-up comedian, and her projects include Netflix’s Mulligan, We Lost Our Human, and Apple TV+’s Dickinson.
Maya Rudolph as Connie and Diane Birch
Maya Rudolph voices hormone monstress Connie and Nick’s mother, Diane Birch. In previous seasons, she also voiced a bath mat, the ghosts of Elizabeth Taylor and Whitney Houston, Principal Barren, and Miss Clinkscales. Rudolph is known for her work in SNL, and since her departure, she has appeared in various movies, such as Bridesmaids, Sisters, Wine Country, and Hubie Halloween, as well as the TV show The Good Place.
Andrew Rannells as Matthew MacDell
Andrew Rannells lends his voice to Matthew MacDell, a gay student who helped Jay when he was questioning his sexual orientation. Rannells is known for his work in musical theater and for his roles in A Simple Favor, The Prom.
Thandie Newton as Mona
Thandie Newton voices hormone monstress Mona, who follows Missy around. Newton has appeared in a number of movies, such as Mission: Impossible 2, Crash, RocknRolla, and Solo: A Star Wars Story, as well as in the TV shows ER and Westworld.
Maria Bamford as Tito the Anxiety Mosquito
Maria Bamford is the voice of Tito the Anxiety Mosquito, a new threat the group will encounter at camp and which will follow them when they go back home. While Bamford is best known for her comedy work, she has voiced a number of characters in various projects throughout her career, such as the TV shows Hey Arnold!, Catdog, Kick Buttowski: Suburban Daredevil, and Adventure Time.
Fred Armisen as Elliot Birch
Fred Armisen voices Elliot Birch, Nick’s father whose favorite activity seems to be to share inappropriate stories and make his children (and their friends) uncomfortable. In previous seasons, Armisen also voiced the ghost of Antonin Scalia, a bus driver, Stavros, and Bob the Hormone Monster. Armisen is best known for his work in SNL and the TV show Portlandia.
Jordan Peele as the Ghost of Duke Ellington
Jordan Peele lends his voice to the Ghost of Duke Ellington, who lives in Nick’s house and often offers him and his friends advice, though he’s not the best at it. Peele has also voiced Jay’s hyper-aware dog Featuring Ludacris and the ghosts of Freddie Mercury, David Bowie, and Prince, as well as Atlanta Claus, a DJ, Missy’s father, and Patrick Ewing. Peele is known for his comedic roles, mostly in the TV show Key & Peele, and for his work as a horror filmmaker, with the movies Us.
Big Mouth Season 4 Guest Stars
John Oliver as Harry, a camp counselor – Oliver is a comedian and political commentator best known for being the host of Last Week Tonight with John Oliver.
Seth Rogen as Seth Goldberg, a camper and Nick’s new friend – Rogen is known for his roles in the movies Knocked Up, Pineapple Express, This is the End, The Interview, and The Disaster Artist.
Zach Galifianakis as Gratitoad – Galifianakis has appeared in The Hangover trilogy, Due Date, Birdman, A Wrinkle in Time, and Between Two Ferns.
Lena Waithe as Lena, one of Missy's cousins – Waithe has appeared in the movies Ready Player One, Bad Hair, and the series Dear White People and Westworld.
Sterling K. Brown as Michael Angelo, Jessi's new boyfriend – Brown is known for his roles in the movies Black Panther and The Rhythm Section, as well as the TV shows Army Wives, The People v. O.J. Simpson: American Crime Story, and This Is Us.
Paul Giamatti – Giamatti is best known for his roles in the movies Saving Private Ryan, Planet of the Apes, Sideways, Cinderella Man, The Illusionist, 12 Years a Slave, and Saving Mr. Banks.
Josie Totah as Natalie, a transgender camper – Totah is best known for playing Stuart Wooten in Jessie and Lexi in Saved by the Bell.
Sinbad as himself – Sinbad is a comedian best known for his comedy specials.
Emily Altman as "Milk", a male camper who is often told to shut up – Altman has worked as a writer for shows like Inside Amy Schumer, Unbreakable Kimmy Schmidt, and Big Mouth.
June Diana Raphael as Devin, a popular girl at school – Raphael has appeared in various movies and TV shows, most notably The Disaster Artist, NTSF:SD:SUV::, Burning Love, New Girl, and Grace and Frankie.
Jak Knight as Devon, Devin’s boyfriend – Knight has worked as a writer for Black-ish and Big Mouth.
Paula Pell as Barbara Glouberman, Andrew’s mother – Pell was a writer for SNL and 30 Rock, appeared in the movie Wine Country, and played Ron Swanson’s mother in Parks & Recreation.
Richard Kind as Marty Glouberman, Andrew’s father – Kind is best known for playing Dr. Mark Devanow in Mad About You.
Seth Morris as Greg Glaser, the perpetually stoned father of Jessi and ex-husband of Shannon Glaser – Morris has appeared in TV shows like Veep, Superstore, and The Good Place in minor roles.
Jessica Chaffin as Shannon Glaser, the mother of Jessi & the unfaithful ex-wife of Greg Glaser – Chaffin has appeared in various projects in minor roles, most notably Zoey 101, where she played Coco Wexler.
Gina Rodriguez as Gina Alvarez – Rodriguez is best known for playing the lead role in the series Jane the Virgin and the movies Miss Bala and Someone Great.
Joe Wengert as Caleb – Wengert appeared in minor roles in shows like Modern Family and New Girl.
Jon Daly as Judd Birch – Daly played various roles in Kroll Show.
Kat Dennings as Leah Birch – Dennings is best known for her lead role in 2 Broke Girls and her roles in the movies Nick and Norah’s Infinite Playlist, Thor, and Thor: The Dark World.
Chelsea Peretti as Monica Foreman-Greenwald – Peretti plays Gina Linetti in Brooklyn Nine-Nine.
Heather Lawless as Jenna "Jay's Mom" Bilzerian, Jay's mother – Lawless is best known for her stand-up performances.
Mark Duplass as Val Bilzerian, Jay’s brother – Duplass appeared in the movies Safety Not Guaranteed, Zero Dark Thirty, Creep, and Creep 2, as well as the TV show The Morning Show.
Paul Scheer as Kurt Bilzerian, Jay’s brother – Scheer is best known for playing Andre in The League and Chuck in The Good Place.
David Thewlis as Shame Wizard – Thewlis is best known for playing Remus Lupin in the Harry Potter film series and Sir Patrick Mordan/Ares in Wonder Woman.
Gil Ozeri as Brad, a couch cushion – Ozeri has worked as a writer for Brooklyn Nine-Nine, Big Mouth, and Happy Endings.
Kristen Bell as Pam, a pillow – Bell played the lead role in Veronica Mars and The Good Place.
Kristen Wiig as Jessi's genitals – Wiig is best known for her work in SNL and for her roles in the movies Bridesmaids, The Skeleton Twins, and Wonder Woman 1984.
Harvey Fierstein as Jerome, an older gay man who lives at Guy Town – Fierstein appeared in Mrs. Doubtfire, Independence Day, and voiced Yao in Mulan.
Jean Smart as the Depression Kitty, a cat employed in the Department of Puberty – Smart’s acting credits include the series 24, Samantha Who?, Legion, and the movie A Simple Favor.
Zachary Quinto as Aiden, Matthew's boyfriend – Quinto played Spock in the movies Star Trek, Star Trek Into Darkness, and Star Trek Beyond, and Oliver Thredson in American Horror Story: Asylum.
Ali Wong as Ali, a pansexual student – Wong played the lead role in the rom-com Always Be My Maybe.
Julie White as Kimberly MacDell, Matthew's mother – White’s acting credits include Transformers: Revenge of the Fallen, Transformers: Dark of the Moon, Lincoln, and A Very Murray Christmas.