Some characters are luckier than others: heroes like Batman or Daredevil are in need of surgery after they are done with a villain. Meanwhile, others have the ability to heal wounds within minutes or even seconds depending on the wounds and strength of their healing factor.
Across different realms of comic book franchises, many characters feature a healing factor. Some are more powerful than others; there are characters that can regrow limbs in seconds while others may not heal fast but they can regenerate from almost nothing and keep going.
Superman
Contrary to popular belief, the Man Of Steel is capable of taking a lot of damage from many sources, including many of Superman's best villains who are able to hurt him without weakening him. Unlike other characters, Superman needs a peripheral to trigger his healing factor. In some stories such as the Reign Of The Supermen, it is a regeneration chamber in the Fortress Of Solitude that allows him to return from the dead.
In other situations, he simply needs to bathe in sunlight and the rays of the yellow sun will heal him quickly. From mortal wounds to being a shriveled husk due to radiation, Superman is able to come back from a lot thanks to the sun.
Vandal Savage
Thanks to a meteorite crashing down thousands of years ago, a caveman became one of the first metahumans. He became an immortal seemingly incapable of aging, but he also became indestructible. This is why Vandal Savage was actually so many historical figures, from Genghis Khan to Julius Caesar.
Though he is not completely incapable of dying, he has been shown to take a lot of damage; his throat being slashed open, bones broken, being poisoned, stabbed, and anything else that can kill a regular man is something that he can survive.
Doomsday
The creature known as Doomsday is capable of regeneration, but that makes him only worse for his enemies. All of the damage dealt on Doomsday only makes him stronger, with the spikes on his body getting bigger and deadlier.
This is why Doomsday was able to kill Superman in one of his most famous comic book arcs of all time. Doomsday has also shown to be impervious to death, always managing to resurrect. He's truly one of the most dangerous villains in the comic world.
The Flash
Whether it's Barry Allen or Wally West, The Flash has the gift of the Speed Force. Like all of the many Speedsters out there, the Speed Force grants them an enhanced metabolism; not only does this make them consume massive amounts of food, but the metabolism can heal major wounds.
A single gunshot becomes a mild inconvenience, severe cuts and bruises heal within hours, and he is capable of sharing his healing with someone else, making The Flash one of the best healers in comics.
Lobo
The last Czarnian named Lobo easily has the most impressive healing factor of the DC universe. He doesn't have to rely on it very much, seeing how he's arguably more indestructible than Superman at times. However, if he is wounded, he can be back to full health in a few minutes or even a few seconds.
Lobo has also been shown to have come back to life from a single drop of blood. In the sadly short-lived prequel series Krypton, Lobo regenerated from a severed arm. This amazing strength is one of many reasons why Lobo is one of Superman's most underrated villains.
Wolverine
In the Marvel world, Wolverine is one of the most famous examples of a superhuman healing factor. Combined with his adamantium skeleton, Wolverine has been through the wringer; explosions, bullet wounds, fire, and so much more. He even fought alongside Captain America in World War II, experiencing some of the worst horrors in human history firsthand.
Similar to Lobo, Wolverine can heal most wounds within seconds or minutes. Even fatalities such as being torn apart by the Hulk or having his entire adamantium skeleton forcibly removed from his body were not enough to stop Logan from healing.
X-23
Also known as the daughter of Wolverine, Laura Kinney inherited her father's healing capabilities, but the gene pool seemed to be stronger with Laura. She can regrow her body parts as well as reattach them to heal quickly much like her father, but she even comments that Logan's healing is slower than her own.
This is just one of many reasons why Laura was the perfect replacement as the new Wolverine in Marvel comics. Laura has come a long way from being a new creation for the X-Men Evolution animated series.
The Hulk
It's hard to even hurt the Hulk, let alone draw blood. But those lucky enough (and foolish enough) to wound the Hulk will be surprised. Much like with his physical strength, the Hulk healing factor becomes even more powerful as he gets angrier.
Hulk is another person who has returned to life after being reduced to nothing but a skeleton. He took on the full might of Wolverine's claws and berserker rage to come out on top, and this same healing factor was ed onto his cousin who became She-Hulk. Bruce Banner is now incapable of dying.
Deadpool
It would not be unfair to label Deadpool's healing abilities as overpowered, but that helps fit his fourth-wall-breaking nature. Wade Wilson has been maimed in many ways that would kill even the top-tier Avengers, but always comes back with a smile and quip on his face.
It's more than just losing limbs too, Deadpool has simply been blood on the floor or a decapitated head and he still manages to heal. Often really quickly too, thanks to the experiments that turned him into an immortal.
The Mask
Swapping from Marvel and DC over to the world of Dark Horse comics, there is the mystical mask of mischief created by the Norse god Loki. Whoever wears this mask transforms into an indestructible and violent cartoon capable of nearly anything.
Most might the 1994 film The Mask starring Jim Carrey. That too showcased that bullets can go right through Stanley Ipkiss while he wears the mask; not only does he show no pain, but he cartoonishly mocks his attackers before healing instantly. Unfortunately, without the mask, the wearer is a regular human being.