Night City's ten street gangs, but no other foes are more intimidating and lethal than the crazed Cyberpsychos that lurk in dark alleyways and abandoned shacks across town. Some are particularly fun and immersive, while others can be a chore to deal with.
These mini-boss fights are part of the Psycho Killer quest line given to V by Regina Jones early in the game that allows players to collect the bounty on 17 total Cyberpsychos by either killing them or knocking them out. Each of these NPCs suffers from Cyberpsychosis, which is a hysteric state caused by too many cybernetic body augmentations. That means every Cyberpsycho in Cyberpunk will have its own set of specialized skills and weapons that players need to figure out how to deal with if they want to turn them in for a reward.
Players can choose to either kill or incapacitate a Cyberpsycho when they come across them by finishing them off with a lethal weapon or knocking them out with a blunt weapon, like V's fists or a baseball bat. Whichever approach gamers choose won't change the reward for the mission, but it will result in a different dialogue between Regina and V. Like any boss encounter, a handful of Cyberpsychos feel challenging but rewarding to defeat, while others can be cheap and annoying enemies to deal with. Here are the best and worst Cyberpyscho fights in Cyberpunk 2077.
[Warning: The following contains SPOILERS for Cyberpunk 2077's side quests.]
Cyberpunk 2077: Best Cyberpsycho Fights
Cyberpsycho Sighting: House on a Hill takes V to a seemingly abandoned house in The Badlands that has been turned into a fortified bunker by a crazed maniac. The compound is littered with mines and drones that scout the area, which V can choose to destroy, disable, or leverage to her advantage giving players multiple ways to take out the Cyberpsycho Russell Greene.
He wields a powerful Shotgun and can dash at V so gamers need to keep their distance, which can be made easier with the System Reset quickhack. After the fight is over, Cyberpunk 2077's environmental storytelling reveals that Russell murdered his entire family after his onset of Cyberpsychosis, which is a disturbing end to a satisfying mini-boss fight.
Cyberpsycho Sighting: Phantom of Night City can spawn some of the best loot in the entire Cyberpunk 2077 quest chain and the fight is exciting the whole way through. The mission begins in the City Center area of Corpo Plaza and will lead V into a room east of the quest marker, where they'll run into Norio Akuhara who wields a Katana and Smart weapons.
After an initial scuffle, Norio will disappear and lead V into a separate room with a gang of other enemies to assist him. Constantly sliding behind cover and whittling Norio and his entourage down with Assault Rifles and Sub-Machine guns is players' best bet. After the fight, Norio will drop a legendary Katana, and the first room V entered from has a box that has a chance to spawn Legendary Mantis Blades.
Cyberpunk 2077: Worst Cyberpsycho Fights
Cyberpsycho Sighting: Blood Ritual has all of the ingredients to be a fantastic mini-boss, but all of that is soiled due to how annoying it is to even find Zaria Hughes to begin the mission. She only spawns in the Northside of Watson after 8 p.m. in-game time, but Regina doesn't give V any indication about that restriction, which can result in players who stumbled upon the mission wasting time investigating the area during the daytime. That's shame considering how creepy the area where she resides is, but any sense of Cyberpunk 2077 players aren't aware of her spawn timer.
Once the fight begins, Zaria constantly rushes at V with her Mantis Blades and lights them on fire every time she lands a blow. The double jump perk, Cripple quickhack, Electrical weapons, and any kind of thermal resistance will make this fight much easier but if gamers begin the battle without these buffs they need to constantly run and gun Zaria down if they don't want to be sliced to pieces.
Finally, Cyberpsycho Sighting: Discount Doc is nearly impossible to complete without using cheap gimmicks to players' advantage. Chase Coley carries around a massive riot shield and is found in the Rancho Coronado area with a few weaker enemies in the vicinity. Chase will continuously bull-rush V and also has an extremely powerful Shotgun capable of dealing lethal damage in two shots.
Players need to first take out all of the weaker thugs in the area before taking on the psycho, which is incredibly difficult with Chase running them down constantly with his shield. The simplest way to complete this mission is to climb up on a nearby roof to pick off Chase's lackeys and then use Cyberpunk's Smart Sniper or Precision Rifle to hit Chase behind his shield. Fighting chase on the ground can be nearly impossible and having to resort to this cheap trick makes this fight much less rewarding than all of the others in Cyberpunk 2077.
