There are thousands of of the Demon Slayer Corps, the organization responsible for protecting humanity from man-eating demons, but some recruits have killed more of the bloodthirsty creatures than others. From high-ranking Hashira like Giyu to newer like Tanjiro, only the best demon slayers have managed to survive long enough to wipe out more than a few of the evil beasts.

With masterful swordsmanship, unmatched bravery, and years of training, these heroes have made the world a much safer place through their efforts. Among these thousands of demon slayers in the series, ten in particular reign supreme as the deadliest and are responsible for decimating the most demons.

10 Mitsuri Kanroji

Her Muscle Strength and Swordsmanship Help Her Take Down Upper Rank Demons Easily

Love Hashira, Mitsuri Kanroji, may have a kindhearted attitude otherwise, but she is ruthless when it comes to fighting villains. With her self-invented Love Breathing style, based around Flame Breathing, she has managed to help take down not just lower level demons, but Upper Ranks like Hantengu.

Mitsuri is the most outgoing and friendly of all the Hashira, making new recruits feel welcome, so it is easy to underestimate how powerful she is, but that is a grave error many demons have made. With eight times stronger muscles than the average human, Mitsuri can destroy any demon unlucky enough to cross her path with ease.

9 Muichiro Tokito

Muichiro Helped Kill the Menacing Upper Rank Demons, Gyokko and Kokushibo

Muichiro is only 14 years old, but has accomplished more than most adult demon slayers could dream of achieving. During the Swordsmith Village arc, Muichiro beat Gyokko, the Upper Rank Five demon, on his own, by beheading the creature using Mist Breathing at a lightning fast speed and destroying him beyond recognition before he could regenerate.

This was not even Muichiro's most astounding kill, because he later contributed to Kokushibo's death. Kokushibo is the Upper Rank One demon, and alongside a group of other Hashira, Muichiro made swift work of the demon. Despite his young age, Muichiro is one of the deadliest demon slayers in the series.

8 Giyu Tomioka

Both Alone and Alongside Others, Giyu Has Vanquished Many High-Ranking Demons Like Rui

Giyu Tomioka is the most reserved and solitary member of the Hashira, but on his own, he has racked up a staggering number of demon deaths. One of his most noteworthy murders was Rui, one of the Twelve Kizuki and Spider Demons, who he quickly decapitated with his Water Breathing Style.

There are many other demons Giyu helped slay along with his fellow Hashira, including Akaza and even Muzan. Although Giyu did not deal the final blow in these encounters, without his contributions, the demons would not have been weakened enough to die. Because of his careful, methodical way of fighting and mercilessness when it comes to evil, Giyu is one of the deadliest demon slayers.

7 Inosuke Hashibira

The Beast Breather Inosuke Killed the Upper Rank Two Demon, Doma, as Well as a Host of Other Evil Creatures

Inosuke is among the most fearless demon slayers, with an animalistic Beast Breathing Style that allows him to cut down vast numbers of demons. He has a bone to pick with one Upper Rank demon in particular, the Upper Rank Two, Doma. Because of Doma, Inosuke's mother died violently, and he grew up alone in the mountains, raised by boars, so he made it his mission to seek vengeance on the heartless being.

Alongside Shinobu and Kanao, Inosuke ensured Doma breathed his last breath, marking one of his greatest kills. Inosuke also killed many lower ranked demons over the years and participated in the final fight against Muzan, making him one of the most proficient killers in the series, blasting through threats with his iconic boar mask and jagged double set of blades.

6 Zenitsu Agatsuma

Due to a Personal Grudge, He Killed an Upper Rank Six Demon, Kaigaku, All on His Own

Zenitsu Agatsuma is one of Demon Slayer's most controversial characters, but he blossomed from a terrified coward to one of the series' most resilient fighters. Zenitsu harnessed his Thunder Breathing, previously only usable to him in his sleep, and killed the Spider Demon son, the Tongue Demon, and eventually, Kaigaku, an Upper Rank Six.

Zenitsu had a personal grudge against Kaigaku since he was to blame for Zenitsu's master, Jigoro's, death, which spurred Zenitsu on to kill the once demon slayer turned demon in a truly badass fashion. The Thunder Breather's transformation was more stark than anyone else's in Demon Slayer, as he morphed from someone who cowered in fear at demons to one of the deadliest warriors in the world.

5 Obanai Iguro

Obanai Substantially Weakened Muzan, Creating an Opening for Others To Kill the Demon King

Obanai Iguro had one of the most Demon Slayer character, suffering abuse, neglect, and mistreatment from his family who became ensnared in a cult, as well as the leader of the cult, the horrific Serpent Demon. Despite all the shortcomings Obanai faced, he trained and practiced to become one of the best Hashira, killing as many demons as humanly possible before his later demise.

Apart from slaughtering a number of lower level demons, Obanai was one of the major players in the final fight with Demon King, Muzan. With his Serpent Breathing, he weakened Muzan substantially, creating the perfect situation for the others to strike and end his life for good. Overall, Obanai proved himself to be capable of bringing even the mightest demons like Muzan to death.

4 Kyojuro Rengoku

Rengoku Destroyed Hordes of Demons on His Own, and ed Down His Breathing Style To Continue His Work

Kyojuro Rengoku, the Flame Hashira, embodied strength that even demons like Akaza took note of. Although he unfortunately did not survive past the events of the Mugen Train arc, his final battle with the Upper Rank Three, Akaza, only further revealed why he is one of Demon Slayer's deadliest threats. With his Flame Breathing and swordsmanship, he moved so fast he was almost undetectable, slicing up demons in rapid fashion.

In his last fight, Akaza begged Rengoku to the evil side instead and put his abilities to better use, but Rengoku refused due to his righteous conscience. Although Rengoku killed many other demons during this arc and before, Akaza unfortunately overpowered him and ended his life, but not before he could train many others, like Mitsuri, to use his Breathing Style to continue his work. In this way, Rengoku's techniques cleverly continued to end demons' lives even after his own death, through the work of others.

3 Gyomei Himejima

Gyomei Decapitated Kokushibo, an Immensely Powerful Upper Rank One Demon

Gyomei is canonically the strongest member of the Hashira, although his everyday personality is characterized by gentleness and meekness. Despite his soft-spoken nature, Gyomei decapitated Kokushibo, the Upper Rank One demon, defeating him when even Yoriichi, the first demon slayer, was unable to.

Gyomei's Stone Breathing is exceptionally effective, and few demon slayers or Hashira can match his level of skill in combat. Although he sadly died battling Muzan, he contributed to the demon slayers' victory over the evil king, cementing his status forever as one of the series' most lethal heroes.

2 Tanjiro Kamado

Tanjiro Has Slaughtered More Upper Rank Demons Than Any Other Demon Slayer

Tanjiro Kamado, had his work cut out for him when he was tasked with saving his sister, Nezuko, from her fate as a demon and triumphing over the Demon King, Muzan, but he rose to the challenge, crushing every demon in his path. Some of Tanjiro's most magnificent kills include the Upper Rank Six demons, Gyutaro and Daki, Upper Rank Four, Hantengu, and Upper Rank Three, Akaza.

Few demon slayers have murdered as many Upper Rank demons as Tanjiro managed to, making him Hashira level in regard to his kills. Most spectacularly of all though, Tanjiro managed to kill the first demon ever Lord Muzan, with teamwork from other demon slayers. Tanjiro began the series as a fairly weak and average human, but his training molded him into a demon's worst nightmare.

1 Yoriichi Tsugikuni

Yoriichi Was Not Only the Deadliest Demon Killer, He Paved the Way for the Demon Slayer Corps Formation

Yoriichi is known as the first demon slayer and the inventor of Breathing Styles, and without him, the Demon Slayer Corps would never have been brought into existence. Tanjiro followed in Yoriichi's footsteps in a multitude of ways, most notably, his Sun Breathing, known as Hinokami Kagura, which was created initially by Yoriichi. Yoriichi definitely deserves to be called Demon Slayer's deadliest demon slayer.

He killed hundreds of demons with his blade and almost killed Muzan singlehandedly, had the Demon King not regenerated at the last moment. Demons cowered in terror at Yoriichi's name, proving the significant negative reputation he had among the creatures. Not only did Yoriichi kill droves of demons himself, he paved the path for others to continue his legacy, making him the most fatal of demon killers in Demon Slayer.