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Season 6 of Diablo 4, Vessel of Hatred, once again offers Uber Mythic Unique items as perhaps the strongest gear you can find in the game. These items are exceedingly rare, found typically as Ancestral 800 Power armor pieces or weapons. With 12 total Mythic Uniques you can find, each has a powerful effect that could be perfect for your character's build.
Mythic Unique items can drop from any major boss or enemy you encounter, but they have the highest chance of appearing in greater difficulties. In World Tier 4: Torment in Diablo 4, you'll have much better luck farming Tormented bosses for a Mythic Unique. It is important to that not all the Mythic Unique items can be used by every class, limiting which ones a character can use.
New Items For All Classes
Discover Universal Mythics For Any Character
Thankfully, some Mythic Unique items work for every class, making them universal gear pieces that anyone can use. The effects of these Uber items are just as potent as ones designed to synergize with specific archetype skills. In fact, 8 of the 12 Mythic Uniques can be equipped by all classes, giving you a wide range of Unique items in Diablo 4 to work into the build for your character.

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The universal Uber Mythic Uniques you can get for all classes include these items:
Mythic Unique |
Item Type |
Unique Effect |
Other Stats |
---|---|---|---|
Andariel's Visage |
Helm |
Lucky Hit: Up to a 20% chance to trigger a poison nova that applies 4,500 Poisoning damage over five seconds to enemies in the area. |
+30.00% Attack Speed, +77 All Stats, +86 Life On Hit, +10% Maximum Poison Resistance |
Doombringer |
One-Handed Sword |
Lucky Hit: Up to a 25% chance to deal 900 Shadow damage to surrounding enemies and reduce their damage dealt by 20% for five seconds. |
+114 All Stats, 10.0% Damage Reduction, Up to 15% chance to heal +530 Life, 35.0% Maximum Life |
Helm |
Gain 20% Damage Reduction. In addition, +4 Ranks for all Skills. |
20.0% Cooldown Reduction, +365 Maximum Life, +18 Maximum Resource, +350 Armor |
|
Heir Of Perdition |
Helm |
Succumb to hatred and earn Mother's Favor, increasing your damage dealt by 60%. Slaughter enemies to briefly steal Mother's Favor from nearby allies. |
+20.0% Critical Strike Chance, +20.0% Lucky Hit Chance, +20.0% Movement Speed, +2 to Core Skills |
Most Uber Mythic Unique items in Diablo 4 can be found when you complete Nightmare Dungeons, Helltides, or other seasonal and world events that take place within the game.
Mythic Unique |
Item Type |
Unique Effect |
Other Stats |
---|---|---|---|
Melted Heart Of Selig |
Ring |
Gain 60 Maximum Resource. When taking damage, 75% is drained as 2 Resource for every 1% of Maximum Life you would have lost. |
15% Damage Reduction (when Healthy), +15% Lucky Hit Chance, +25% Movement Speed, 15% Resource Generation |
Ring Of Starless Skies |
Ring |
Spending your Primary Resource reduces the Resource cost of your Skills and increases your damage by 10% for three seconds, up to 50%. |
+17.5% Attack Speed, +12.5% Critical Strike Chance, +12.5% Lucky Hit Chance, +2 to Core Skills |
Shroud Of False Death |
Chest Armor |
If you haven't dealt damage in the last two seconds, gain Stealth and 40% extra Movement Speed. |
+111 All Stats, +333% Damage on Next Attack After Entering Stealth, +222 Maximum Life, 11.1% Resource Generation |
Tyrael's Might |
Chest Armor |
While at full Life, your Skills unleash a divine barrage dealing 195 Damage on hit. |
20.0% Damage Reduction, +16.5% Movement Speed, +60.0% Resistance to all Elements, +7.5% Maximum Resistance to all Elements |
You may notice that many of the Mythic Unique items available in Season 6 return from different seasons of content in Diablo 4. Although some items will be familiar, their effects may have changed, making them worth hunting down a second or third time. Those looking to have multiple characters in a Vessel of Hatred world may want to find the same item more than once to help make all their builds as strong as possible.
New Items For Specific Classes
Find Weapons Only Certain Characters Can Wield
The only restriction to Mythic Unique items is that some Uber artifacts are weapons that can only be wielded by a specific class. For example, one Mythic Unique could be a polearm, which is a type of tool only the new Spiritborn class in Diablo 4 can use. There are four total Mythic Uniques locked to class restrictions, including:
Mythic Unique |
Class |
Item Type |
Unique Effect |
Other Stats |
---|---|---|---|---|
Ahavarion, Spear Of Lycander |
Druid, Sorcerer |
Staff |
Gain a random Shrine effect for 20 seconds after killing an Elite enemy. Can only occur once every 30 seconds. |
+18% All Stats, +33% Movement Speed, +66% Resistance to All Elements, Up to 15% chance to Restore 66% of Primary Resource |
Nesekem, The Herald |
Spiritborn |
Glaive |
Every five seconds, you randomly mark a nearby enemy. Marked enemies are Vulnerable, and your attacks against them are guaranteed to Critically Strike and Overpower. Hitting a marked enemy 10 times clears the mark from them. |
+200 All Stats, +464 Maximum Life, +250% Critical Strike Damage, +450% Overpower Damage |
Shattered Vow |
Barbarian, Druid, Spiritborn |
Polearm |
Enemies afflicted by more Damage over Time than remaining Life are executed. |
Up to 15% Chance to become Berserking, +29.6% Attack Speed while Berserking, +444.4% Damage over Time, +444 Maximum Life |
The Grandfather |
Barbarian, Necromancer |
Two-Handed Sword |
Increases your Critical Strike Damage by 100%. The other properties of this weapon can roll higher than normal. |
+150 All Stats, +300% Damage, +662 Maximum Life, +20 Maximum Resource |

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Like every weapon and armor you find in Diablo 4, Mythic Unique artifacts also have Damage per Second and Armor qualities that come standard to the gear. These stats usually dwarf pre-existing armor pieces or weaponry, matching the total Ancestral Power typical of these items. However, certain Legendary or normal Unique items may have higher attack or defense stats than even these Mythic tools.
How To Craft Mythic Unique Items In Season 6
Spend Money And Break Down Items
Although you could craft Mythic Unique items in Season 5, the methods to do so have changed somewhat in Vessel of Hatred. The process has been made slightly easier, allowing more players to gain specific Mythic Uniques they want from crafting. You'll still need the resource called Resplendent Sparks to make Mythic Uniques of your own.
You can gain 1 Resplendent Spark by salvaging a Mythic Unique item you already have in your possession. You can turn in two Resplendent Sparks and 50,000,000 Gold to a Blacksmith to gain a Mythic Unique Cache. This Cache can drop any of the 12 Mythic Unique artifacts mentioned before, but you have to rely on chance to get the one you want most.
Those who are concerned about salvaging their only Mythic Unique for Resplendent Sparks should check out the above video by YouTube creator RageGamingVideos, who shows great places to farm another depending on your character's class!
Those looking to craft a specific Mythic Unique can take 2 Resplendent Sparks and 5,000 Gold to a Jeweler NPC to make exactly what they need. However, this vendor will only craft a Mythic Unique when you have certain Runes gained from other crafting recipes. You may have to salvage other important items to make the Runes needed in the creation of a certain artifact.
Check all your options and see what resources you have to spend on various crafting methods. Once you understand what all the Uber Mythic Unique items do in Diablo 4 Season 6, you'll have a better idea of which ones to invest in when trying to craft one on your own.
Source: RageGamingVideos/YouTube
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