Resident Marvel sorcerer a seemingly unstoppable villain.
Since the establishment of the Marvel Universe in the early 1960s, Stan Lee, Jack Kirby, and a host of other writers and artists who followed, have used various easter eggs including name drops, ing characters, superhero team ups, and even distinct artifacts to tie the massive universe together. These connections have made the world feel much more of an engaging experience for fans while also making the superhero environment feel lived in.
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Even with the original Strange Tales title, Doctor Strange has never been a major superhero crossover comic on the same levels of rather than get involved in the superhero affairs. But, there have been occasional instances where certain elements of Strange's realm would seep into the greater world outside his Sanctum Sanctorum home. One of the good doctor's key powers have become the Crimson Bands of Cyttorak, (first used in Strange Tales #124) which are invoked through the ancient being itself and largely act as an imprisonment (binding) of objects and opponents as well as lifts spells. However, little did Strange know that the crimson bands would eventually end up giving birth to one of his home world's greatest modern villains.
In 1965, Stan Lee and Jack Kirby would introduce one of the X-Men's most powerful and persistent foes Cain Marko a.k.a. the Unstoppable Juggernaut. Juggernaut's first appearance in Uncanny X-Men #12 would reveal that the brash Cain and his more cautious step brother Charles Xavier both served in the Korean War together. While serving in Asia, Cain would stumble upon the ancient lost temple of the demon Cyttorak. Refusing to give in to his brother's warnings, Cain would grab a hold of the temple's centerpiece ruby which would grant its beholder the power of the crimson bands of Cyttorak. A vast amount of the Juggernaut's great power is completely derived from ruby Cain had disturbed years prior in Cyttorak's temple. With the incredible power of Cyttorak at his disposal, Juggernaut would go on to torment the X-Men and Marvel's extended library of superheroes for years.
While Juggernaut has been featured onscreen, the films have largely ignored the Cyttorak connection. Part of this is simply due to Marvel Studios having ownership of Doctor Strange and another part in 20th Century Fox likely wanting to streamline the Juggernaut by making Cain a mutant.