Red vs. Blue: Zero is the newest season of the Halo-inspired Red vs. Blue web series. The new season concerns a ragtag group of recruits who form Shatter Squad. Together, Shatter Squad must stop an enigmatic figure known as Zero. While earlier seasons relied more heavily on the Halo content that inspired it, Red vs. Blue: Zero is a bigger departure than what's been seen previously.
Still, that doesn't mean Red vs. Blue: Zero has completely abandoned its Halo beginnings. The games' iconic Warthog vehicles are still featured prominently in the show, and most of the main characters are wearing Halo armor sets seen in previous games. A few of these skins come from newer cosmetics seen in Halo: The Master Chief Collection. Other assets are pulled from non-Halo games, like the cancelled Paragon from Epic Games.
So, while Red vs. Blue: Zero contains Halo elements, it doesn't appear to connect directly to any Halo games. This is pretty similar to how most seasons of the web series are, although a small mini-series related to Halo: Reach released to coincide with the game in 2010. This was more like a string of meta episodes, though, in which characters from the Red Team prepared to move from Halo 3 to Halo: Reach.
Is Red Vs. Blue: Zero Considered Canon?
While Red vs. Blue: Zero doesn't connect to Halo lore that much (at least, not in the three episodes Screen Rant previewed) some fans may be wondering if it's still considered canon. So far, Red vs. Blue has never been considered official Halo canon - it's more like an ode to the Halo franchise than a story canonically related to it. Red vs. Blue: Zero appears to keep with this tradition as being a non-canon story set within the Halo universe.
For long-time fans of the web series, this answer shouldn't be too surprising. Halo media tends to work outside the main narrative, with the Halo Showtime series reportedly ignoring story points from the games. Even the Red vs. Blue mini-series from 2010 promoting Halo: Reach is considered non-canon. This doesn't mean Halo fans won't appreciate the new season, however. Like previous seasons of Red vs. Blue, there are still lots of references to the video game franchise that inspired it.
Red vs. Blue: Zero began streaming on November 9th. The new season introduces new characters and plot twists, but isn't directly connected to Halo. Even though it's more of a standalone series and considered non-canon, fans of the show, and of Halo in general, should still enjoy it.