Summary
- Chase and Cameron's relationship in House, M.D. started as a flirtation and turned into a "friends with benefits" situation before they eventually got married.
- Their marriage ended due to strain caused by Chase adopting some of House's bad qualities and a disagreement over ethics, ultimately leading to their divorce.
- Cameron itted to having doubts about her love for Chase and brought divorce papers to the hospital, officially ending their marriage in House, M.D.
House, M.D. featured many romantic relationships over its eight seasons and 177 episodes, and one of the most significant romances in the show was between Dr. Robert Chase and Dr. Allison Cameron. Jesse Spencer and Jennifer Morrison played Chase and Cameron, respectively, and their characters were introduced in the pilot episode. Chase, a surgeon, and Cameron, an immunologist, were a part of Dr. Gregory House's diagnosticians team at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey. Each episode features the group of doctors working closely together to diagnose patients, and over time, Chase and Cameron's connection grew strong.
Chase and Cameron flirted with one another at the beginning of the Fox medical drama television series, but by season 3, they had entered a "friends with benefits" relationship. Chase wanted more out of it, but Cameron broke things off with him when he suggested they actually date. After much pushing on Chase's end, they got back together in the season 3 finale, and the couple was married by the end of season 5. Sadly, Chase and Cameron's marriage was not built to last, and they ended up getting a divorce in House, M.D.
Cameron Leaves Chase After She Realizes He's Become More Like House
Cameron and Chase's relationship became strained in House, M.D. season 6, which ultimately led to their divorce. After working so closely with House, played by Greg Laurie, for so long, Cameron believed that Chase had taken on some of his bad qualities. In episode 4, the team was treating an African dictator named President Dibala, and Chase, who didn't agree with his morals or policies, faked the results of his blood test. As a result, Dibala was not diagnosed properly, and he died.
A couple of episodes later, Cameron learned of her husband's actions, and she suggested they resign from the hospital together to get away from it all. Chase initially agreed but later changed his mind. Cameron did not let Chase's refusal to leave stop her, and she set off on her own in House, M.D. season 6, episode 8.

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Cameron & Chase Officially End Things In House Season 6, Episode 17
House, M.D. season 6, episode 17 to give closure to Chase and Cameron's romance. The two characters got into an argument, reminisced on their relationship, and spent one last moment together. Even though Chase killing President Dibala was the beginning of the end for them, Cameron itted that other things led to their breakup. She was unsure if she ever really loved him, and she had her own issues to work through before she could commit to someone. As a result, Cameron brought divorce papers to the hospital, which Chase signed, and that was the end of their marriage in House, M.D.