New information about the The Equalizer and its sequel, had reportedly been brought on to write the script, and has stated in an interview that Kraven will "come face-to-face with Spider-Man."
The character first appeared in The Amazing Spider-Man #15 which came out in August 1965, and he quickly become one of Spider-Man's long-standing archenemies. Kraven is most well-known for the 1987 storyline "Kraven's Last Hunt." The story essentially has Kraven hunting and capturing Spider-Man, then donning his costume, in order to prove that he can be the better superhero. Their roles are switched once Spider-Man escapes, and the hunter becomes the hunted. The story is critically acclaimed and believed by many to be one of the best Spider-Man stories ever.
According to an exclusive from The Illuminerdi, a casting grid has revealed details about what Sony is picturing for the Kraven the Hunter solo film. The character is referred to as "a maniacal big game hunter," a direct reference to the comic book version. But more importantly, the information specifically states that he is hunting Spider-Man. Other details revealed are that they are looking for someone who is a Bourne-type and in their late thirties or forties.
Though separate from the Marvel films, so this relationship may remain one-sided. This would allow anything that happens to Spider-Man in Marvel films to affect Sony's films, but not necessarily the other way around.
If this character breakdown becomes a reality, Kraven will be directly connected to Spider-Man, who is arguably currently at the center of the MCU. It seems unavoidable that it will influence and shape the surrounding MCU characters, possibly opening up for future appearances in their films. Ryan Coogler stated that he tried to as the director Jon Watts wants, we will have to wait and see.
Source: The Illuminderdi