When BOTW sequel, particularly its open-world map and the settlements within it. TOTK is set to release on May 12 of next year, so it may be some time until fans see whether Kakariko Village will stay the same unless it's shown in a new trailer.
Kakariko Village is a classic location that's appeared in multiple Zelda games. It first appeared in A Link to the Past, where it is the largest settlement in the game and where Link will find Sahasrahla, the village elder. In Breath of the Wild, it's the home of the Sheikah clan, a group of people dedicated to protecting the royal lineage of Hyrule. It contains a few small shops along with a Goddess Statue that Link can obtain hearts and stamina pieces from in exchange for Spirit Orbs. It's also the home of Impa, a character who has appeared multiple times throughout Legend of Zelda's split timelines, and who helps drive Breath of the Wild's main questline.
It's reasonable to assume that every Breath of the Wild location - settlement or not - will experience some amount of change in TOTK. However, Kakariko Village in particular could change due to both the many iterations it's had across the Zelda series and because of its importance to BOTW's story. In addition, TOTK's altered landscape may offer the most drastic change yet for Kakariko Village. It's possible that it will be on one of the floating islands that dot Hyrule's skies, giving TOTK a unique version of one of Zelda's most frequently-recurring locales. It could also change in other ways, but becoming one of Hyrule's floating islands has unique possibilities that Kakariko may not have if it stays on the ground, and this may be the best option for it.
Zelda's Kakariko Village May Change Drastically From BOTW To TOTK
If Kakariko Village does float up into the BOTW sequel's transformed skies, even without Farosh, it could change quite a bit. It may not become one cohesive island, but several small ones, leaving the houses and shops unconnected aside from a series of bridges. It may also sustain no small amount of damage from the shift, and some sections such as the pumpkin farm may be absent. It's also possible that Kakariko Village will be used as a hub of sorts for the floating islands, retaining its purpose from BOTW but in a different form. For example, Kakariko may give Link several side quests and challenges related to the floating islands, and the shops' inventories might change to sell goods found throughout them and clothes and equipment to help him explore the skies.
It's also possible that Kakariko Village will stay on the ground, in which case Zelda: Tears of the Kingdom's timeline details could shake things up in a different way. It might have a different layout or grow in size, especially with the restoration efforts that Link and Zelda set out to do in BOTW's ending. The biggest changes may even be the most typical ones; just like if it was in the air, Kakariko may gain different goods in the shops or new quests from the inhabitants, but ones unrelated to the floating islands.
Regardless of whether it becomes a floating island or stays anchored on the ground, another big change for Kakariko could be its role in TOTK's main questline as opposed to BOTW's. The antagonist of TOTK is presumed to be the withered mummy that Link and Zelda stumble upon deep in a cave, and has some connection to Calamity Ganon since it exudes his Malice. Since the Sheikah are Ganon's enemies and have opposed him for over 10,000 years, it's possible that TOTK's antagonist - whether it's Ganon or multiple villains - will destroy Kakariko. If so, Link may defend it from the villain's forces, or failing that, rebuild and expand it similar to BOTW's Tarrey Town. This idea sounds particularly exciting if Kakariko Village becomes one of Legend of Zelda: Tears of the Kingdom's floating islands, and can help make it even more unique than it would be otherwise.