As Spider-Man tries to cope with the fact that a man named Ethan Edwards a.k.a. Virtue has stolen his spotlight after he becomes a reporter for the Daily Bugle, a lesser-known villain has grown fond of snow... and it's not the kind one builds a snowman with.
Spider-Man's list of outrageous as well as WTF villains to count and in Reginald Hudlin, Billy Tan, and Steve Mcniven's Marvel Knight's Spider-Man #16, another one is added to the list as he physically transforms into the very drug he's addicted to.
Before becoming cocaine, In Hudlin, Tan, and Mcniven's comic Marvel Knights Spider-Man #15, while Spider-Man searches for his stolen wallet with the help of Virtue, a man named Carl Creel a.k.a. the Absorbing Man decides to work for Leland Owlsley-the leader of a criminal empire to ensure he has a sufficient supply of cocaine. After visiting an abandoned apartment in Queens, Creel and one of Owlsley's henchmen drive over a bridge and find they're being targeted by the Punisher after a bullet pierces the windshield and hits Creel's chest. As Creel begins to bleed out, the woman working for Owlsley tells him to turn into the bullet to stop the bleeding because Creel's superpower is to absorb and become any material. A clever trick... but returning to human form is still a problem. Until a fellow thug offers a solution: snort a bag of cocaine, so he can become it, and the bullet fragments will fall out of his powdery body. But after Creel snorts and becomes the cocaine, something happens that he does not expect.
After snorting and becoming the cocaine, a group of Owlsley's henchmen step into the room with two huge fans and blow his body around the room-covering everything with Creel Cocaine. After the henchman scrape and collect Creel Cocaine from the walls, furniture, and decorations, they package him up and plan on cutting and selling him. It's clear that Owlsley has planned on Creel becoming cocaine because he already has buyers lined up and ready to go.
Maybe, Creel should have been there when Uncle Ben told Spider-Man, "With great power, comes great responsibility," because his irresponsibility has become his downfall. In the Absorbing Man's case; not only is he what he eats, but he is also what he snorts.