Honestly I think you could make a great show out of any of the characters. Each one has their own characteristics and quirky ways. I'm a big fan of Big Bang Theory and Young Sheldon. I would watch a new show about any and all of the main show characters. It's all in the writing, good writing with unique characters equals a good show. I'd like to see stories of all the characters when they were younger up until they came to meet Sheldon. Especially the guys, I think they would be hilarious. We definitely need more comedies with quirky unique characters. Here's to hoping we get to see how, Leonard, Raj, and Howard grew up and became their characters on BBT.