Airing from 1994 to 1998, Spider-Man: The Animated Series was a cornerstone of superhero storytelling. Its episodes brought Peter Parker’s dual life as a student and superhero into vibrant, animated form. The show tackled mature themes such as loss, responsibility, and redemption while remaining accessible to a younger audience. One of the series’ standout elements was its voice cast. Marvel didn’t just rely on unknowns; they recruited renowned actors and TV legends to bring their characters to life.

15 David Warner Played Herbert Langdon

Herbert Langdon Appeared In 12 Spider-Man: TAS Episodes

David Warner, best known for Tron and Titanic, lent his distinguished voice to Herbert Langdon, a prominent scientist in Spider-Man: The Animated Series. Langdon was a key figure in season 2 and its exploration of genetic mutation. Warner’s gravitas gave the role a depth that elevated these storylines. His experience with villainous or morally gray characters made him a perfect choice for Langdon’s intellectual and calculating demeanor. Warner’s ability to balance intellect with menace left a lasting impression, even in his brief appearances. Warner also appeared in Batman: The Animated Series as Ra's al Ghul.

14 Joan Lee Played Madame Web

Madame Web Appeared In 14 Spider-Man: TAS Episodes

Joan Lee, the wife of Marvel Comics icon Stan Lee, voiced the enigmatic Madame Webb, a recurring mentor figure in Spider-Man: The Animated Series. Madame Web was a mysterious and powerful presence, often appearing to guide Spider-Man through his greatest challenges, including his pivotal journey into the Spider-Verse. Lee’s calm, otherworldly delivery made her portrayal of Madame Webb unforgettable. Her connection to Marvel history as Stan Lee’s wife added an emotional layer, with her performance becoming a legacy-building moment. Her role remains one of the show’s most poignant casting choices.

13 Hank Azaria Played Eddie Brock

Eddie Brock Appeared In 8 Spider-Man: TAS Episodes

Before he became a household name as one of the principal voice actors on The Simpsons, Hank Azaria voiced Eddie Brock in Spider-Man: TAS, the journalist who transforms into Venom. Eddie Brock’s jealousy of Peter Parker and his ultimate corruption by the symbiote were central to some of the show’s most intense arcs. Hank Azaria brought a mix of charisma and simmering resentment to the role, making Eddie Brock a compelling rival for Spider-Man. His transformation into Venom was chilling, and his performance captured the character’s tragic fall from grace, crafting the most memorable villain from Spider-Man: The Animated Series.

12 Mark Hamill Played Hobgoblin

Hobgoblin Appeared In 7 Spider-Man: TAS Episodes

Mark Hamill is best known as Luke Skywalker in Star Wars and for his iconic role as the Joker in Batman: The Animated Series and beyond. However, Hamill also voiced the Hobgoblin in Spider-Man: TAS. This villain’s chaotic and sinister personality suited Hamill’s penchant for theatrical, over-the-top performances. Hamill’s interpretation of Hobgoblin made the character a standout antagonist, rivaling even the Green Goblin’s showstopping battle in Spider-Man: The Animated Series. His chilling laugh and unpredictable demeanor added layers to the role, demonstrating Hamill’s unparalleled ability to bring dynamic comic book villains to life.

11 Sandra Bernhard Played Sarah Baker

Sarah Baker Appeared In Spider-Man: TAS Season 4, Episode 5 “Partners”

Comedian and actress Sandra Bernhard voiced Sarah Baker in Spider-Man: The Animated Series, a ing character who was in a relationship with Scorpion and sought to find a cure for him. While Baker wasn’t a central figure, Bernhard’s sardonic humor and sharp delivery made the character memorable. Sandra Bernhard’s performance brought a unique energy to Spider-Man: The Animated Series, adding personality to a minor role. Her inclusion highlighted how the show consistently cast notable talent, even for less prominent characters.

10 Robert Hays Played Iron Man

Iron Man Appeared In 4 Spider-Man: TAS Episodes

Before the Marvel Cinematic Universe made Iron Man a household name, Iron Man made a thrilling appearance in Spider-Man: The Animated Series. He was voiced by Robert Hays, who is best known for his role in Airplane! and also voiced Shell Head in his own cartoon, Iron Man: TAS. Hays’ version of Tony Stark was confident, witty, and full of swagger, adding depth to Spidey’s interactions with the larger Marvel Animated Universe. Robert Hays’ portrayal brought an early glimpse of Iron Man’s charm and complexity, setting the stage for the character’s later prominence.

9 Martin Landau Played Scorpion

Scorpion Appeared In 11 Spider-Man: TAS Episodes

Academy Award-winning actor Martin Landau provided the voice for Scorpion, one of Spider-Man’s most fearsome adversaries. Landau's commanding voice amplified Scorpion’s raw strength and vengeful motives, which lent gravitas to the character’s struggles throughout Spider-Man: The Animated Series. Landau’s experience as a dramatic actor added unexpected nuance to Scorpion, transforming what could have been a one-dimensional villain into a tragic figure. His involvement demonstrated the show’s commitment to elevating its storytelling. Landau only voiced the villain for four episodes before being replaced by Richard Moll.

8 Nichelle Nichols Played Miriam

Miriam Appeared In 2 Spider-Man: TAS Episodes

Star Trek legend Nichelle Nichols voiced Miriam the vampire Queen in Spider-Man: The Animated Series. Miriam is the mother of Marvel’s vampire hunter Blade, who in the comics is known as Vanessa. Miriam’s sophisticated and menacing presence was brought to life by Nichols’ iconic voice, adding gravitas to her character’s role in the series. Nichols’ performance stood out for its elegance and intensity, proving that her talents extended far beyond Star Trek. Her inclusion added depth to the supernatural elements of the show and is one of several Star Trek alumni to appear.

7 Alfonso Ribeiro Played Randy Robertson

Randy Robertson Appeared In 2 Spider-Man: TAS Episodes

The Fresh Prince of Bel-Air star Alfonso Ribeiro voiced Randy Robertson, the son of Daily Bugle editor Robbie Robertson. Randy was a rebellious and immature teenager who became involved in a gang led by Tombstone. Randy only appeared in two episodes of Spider-Man: TAS, but had a highly emotive storyline, in which his father, the Daily Bugle’s Robbie Robertson, reaffirmed his love for his son. His performance highlighted the importance of Peter’s connections outside his superhero identity, enriching the show’s portrayal of Spider-Man’s personal life.

6 Malcolm McDowell Played Whistler

Whistler Appeared In 4 Spider-Man: TAS Episodes

Malcolm McDowell voiced Whistler in Spider-Man: The Animated Series, a vampire hunter and mentor to Blade. McDowell is known for his roles in as Alex in A Clockwork Orange and the titular Roman Emperor in Caligula. His deep, authoritative voice perfectly suited Whistler’s grim and determined personality. McDowell’s involvement added an extra layer of intensity to the Blade storyline, showcasing the show’s ability to attract high-caliber talent. His portrayal remains a standout moment in the series’ exploration of Marvel’s darker characters. McDowell voiced the character for two episodes and was subsequently replaced by Oliver Muirhead.