The Last Man on Earth is a fox comedy series set in a post-apocalyptic world where a virus has wiped out nearly all human life - at least, that's what Phil Miller believes. Heading on a cross-country journey to find other survivors, Phil nearly succumbs to hopelessness until he finds a woman named Carol, who suggests the two attempt to repopulate the Earth. Soon enough, more and more humans are found alive, slowly building new communities - but Phil seems to have trouble acclimating to the new societal order.