The Walking Dead has never had a problem with killing major characters. From the start in the comics, major characters like Shane and Lori died, and in the comics, everyone was shocked when characters like Carl Grimes died, even though he lived in the comics. Only a few people who lived to the end, such as Carl in the comics, and Daryl Dixon will live to the end of the TV series.
Daryl Dixon never appeared in the comics, and there was not a comparable counterpart, either. That might be part of why Carl lived to the end of the comics, while Daryl will make it to the end of the main TV series. However, in the comics, some massive character deaths shocked readers.
Amy's Death
One of the most shocking early deaths in The Walking Dead comics was Amy. This happened on the TV show as well, as Amy's death pushed Andrea to her fate on TV and her eventual role as a hero in the comics.
Amy was traveling with Andrea and Dale when they met up with the survivors. In a zombie attack on the camp, Amy ended up infected, and Andrea had to take her sister down after her death.
Shane's Death
The death of Shane in the comics and the TV show were different. In the TV show, Shane lived much longer than he did in the comics. However, his death was the same in both cases. Shane betrayed Rick in The Walking Dead and tried to kill him.
He wanted to get rid of Rick because he had fallen in love with Lori. In the TV show, Rick killed Shane, but in the comics, it was a young Carl who killed Shane to protect his dad at the end of the comics' first volume.
Carol's Death
Carol and Andrea basically switched places in the TV show, with Carol becoming the tough survivor on TV while that was Andrea in the comics. Carol, in the comics, was depressed and never was able to make it on her own after her abusive husband's death.
In The Calm Before, Carol wanted to enter a relationship with Lori and Rick and took her own life by a zombie when Lori rejected it.
Tyreese's Death
Daryl was Rick's right-hand man for much of The Walking Dead TV series, but in the comics, it was Tyreese. In the TV show, Tyreese showed up but was very different. He was a pacifist traveling with his younger sister.
In the comics, he was a strong man who remained protective of his daughter. However, it was Tyrese that died at The Governor's blade, a scene changed to Hershel on the TV series.
Lori Grimes' Death
Lori Grimes died in both the comics and in the TV show at the prison. However, the manner of death was horrifically worse in the comics. In the TV show, she died giving birth, and Carl had to finish her off.
In the comics, she delivered Baby Judith, and then The Governor gunned both Lori and Baby Judith down in one of the comic's most brutal scenes. The moment haunted Rick, who hallucinated speaking to her on the phone for several issues after her death.
Hershel's Death
In The Walking Dead TV show, Tyreese was decapitated by The Governor instead of Hershel. However, that was just a minor switch because Hershel also died at the hands of The Governor.
Instead of getting decapitated, The Governor shot Hershel in the head during the siege and battle at the prison. This also led to another change, as The Governor also died when he was shot in the head after this moment. Hershel remains one of the most missed Walking Dead characters.
Morgan's Death
Morgan not only survived The Walking Dead TV show, but he was one of the headliners of Fear of the Walking Dead and has remained hard to kill ever since. In the comics, he didn't make it out alive.
Morgan and Michonne had a relationship in the comics, which made his death more tragic. He died in No Way Out when The Scavengers caused his death, and Michonne had to finish him off.
Dale's Death
Dale had been around since almost the start, but his time came to an end in Fear the Hunters. While The Hunters were the villains in this book, it was Dale who died at the end after he was bitten in the shoulder by zombies.
With Dale knowing he was dying, he had the Hunters eat his "tainted meat." This was a scene saved for Bob on the TV show. Instead, Dale died much sooner as he wanted off the show after AMC fired showrunner Frank Darabont.
Abraham's Death
Abraham died differently in the comics and the TV show as well. On the TV show, Nurse Denise Cloyd died with an arrow to her head at a shocking moment. In the comics, Abraham took the arrow into his eye in the exact scene that saw Denise's death.
In the TV show, Abraham died at Negan's hands instead, during the campfire scene that fans feared from the comics. It was a way that the TV show fooled viewers, having Abraham die instead of Glenn, only to swing the bat one more time after his death.
Glenn's Death
Glenn died the same in The Walking Dead comics and the TV show, and in both cases, it was a shocking moment that hit fans hard.
In the TV show, Negan had everyone in a circle, and he beat Abraham to death, making fans think Glenn would be spared. However, in both cases, Negan also beat Glenn to death with the bat in front of his pregnant wife, Maggie.