Despite starring in 1997's Anaconda, Jennifer Lopez didn't return for the sequel, and here's why. Many essays, and even some books, have been written to extol the merits and joys of watching a good or great film. Countless award shows exist to celebrate such films - but for the right viewer, just as much enjoyment can be derived from a movie that's enjoyably bad. Anaconda is most definitely a "so bad it's good" movie, and today sports a cult following. A big factor in that is its recognizable cast, top of the list being Jennifer Lopez.
In addition to J. Lo, Anaconda also includes appearances by rapper/actor Ice Cube, Hollywood legend Jon Voight, 1980s mainstay Eric Stoltz, former MCU's Mobius himself, Owen Wilson. That's a cast most movies would love to have, even if people like Lopez, Trejo, and Wilson were still on their way up in Hollywood at the time. A box office hit, Anaconda spawned a franchise, with four sequels released to date, and a reboot on the way.
Sadly, none of the Anaconda sequels would see a return to the star power of the original, with neither Lopez or any other of the above listed actors coming back. While an exact reason for Lopez's lack of sequel participation has never been confirmed, what happened seems pretty clear. By the time Sony decided to make Anaconda 2, officially titled Anacondas: The Hunt for the Blood Orchid, Lopez had become far too big a star to bother with a B-movie sequel.
It's unclear why Sony waited until 2004 to make a sequel to Anaconda, since as mentioned, it was a hit. That said, they did wait, and by 2004, Lopez was one of the biggest movie stars in the world. It's likely she wasn't even asked to return for Anaconda 2, as Sony had to know she'd refuse. Plus, even if she had surprisingly agreed to come back, Anaconda 2 had a much smaller budget than the original, and the movie likely couldn't afford to pay Lopez what she'd probably have asked for.
It's worth noting, though, that even without Jennifer Lopez, Anacondas: The Hunt for the Blood Orchid was a box office success. Although to be fair, its smaller budget helped make that profit possible. Following Anaconda 2 though, the Anaconda franchise went direct to video, making it basically impossible Lopez would ever consider returning going forward. Then again, considering one of the animatronic snakes malfunctioned on Anaconda's set and actually attacked her, it's perhaps for the best that J. Lo stayed away from massive snakes from then on.